Joseph J Schroeder Selected Research

safingol (sphinganine)

7/2010	Induction of apoptosis by sphingosine, sphinganine, and C(2)-ceramide in human colon cancer cells, but not by C(2)-dihydroceramide.
11/2006	Evaluation of sphinganine and sphingosine as human breast cancer chemotherapeutic and chemopreventive agents.
1/2006	Sphinganine causes early activation of JNK and p38 MAPK and inhibition of AKT activation in HT-29 human colon cancer cells.
5/2002	Sphingoid bases and ceramide induce apoptosis in HT-29 and HCT-116 human colon cancer cells.

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Joseph J Schroeder Research Topics

Disease

3	Colonic Neoplasms (Colon Cancer) 07/2010 - 05/2002
2	Carcinogenesis 01/2019 - 05/2002
2	Breast Neoplasms (Breast Cancer) 01/2019 - 11/2006
1	Neoplasms (Cancer) 01/2019

Drug/Important Bio-Agent (IBA)

5	SphingosineIBA 01/2019 - 05/2002
4	safingol (sphinganine)IBA 07/2010 - 05/2002
3	SphingolipidsIBA 07/2010 - 05/2002
2	N-acetylsphingosineIBA 01/2019 - 01/2006
2	DNA (Deoxyribonucleic Acid)IBA 07/2010 - 05/2002
2	GlycosphingolipidsIBA 07/2010 - 05/2002
2	SphingomyelinsIBA 07/2010 - 05/2002
1	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2019
1	p38 Mitogen-Activated Protein KinasesIBA 01/2006
1	LipidsIBA 05/2002
1	ChromatinIBA 05/2002
1	DiphenylamineIBA 05/2002
1	CeramidesIBA 05/2002